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The type of habitats most likely to carry infective bacteria includes muddy riverbanks, ditches, gullies, and muddy livestock rearing areas where there is a regular passage of wild or farm mammals. Read about living with pain. On infection the microorganism can be found in blood and cerebrospinal fluid CSF for the first 7 to 10 days invoking serologically identifiable reactions and then moving to the kidneys. Differential diagnosis list for leptospirosis is very large due to diverse symptoms. The MAT microscopic agglutination testa serological test, is considered the gold standard in diagnosing leptospirosis.

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A brief history of epidemic and pestilential diseases. Zoonoses and Public Health. It is estimated that seven to ten million people are infected by leptospirosis per year. Leptospiral infection in humans causes a range of symptomsand some infected persons may have no symptoms at all. Joint replacement operations are often needed. As a large panel of different leptospira must be subcultured frequently, which is both laborious and expensive, it is underused, especially in developing countries. The disease was first described by Adolf Weil in when he reported an "acute infectious disease with enlargement of spleenjaundiceand nephritis.

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