Exposure to light at night, as it occurs in night shift workers, has been shown to reduce melatonin levels. Scand J Work Environ Health. Brazilian Step Sister 1. Oncostatic effects of the pineal gland. In humans, melatonin secretion is regulated by the hypothalamus, which receives environmental light signals from the retina via the retino-hypothalamic tract.
Future studies in this area will help to clarify whether melatonin has a role in future cancer prevention strategies.
Circulating Melatonin And The Risk Of Breast And Endometrial Cancer In Women
Only two prospective studies have evaluated the associations, one of which did not find an increased risk, 81 whereas the other one described a significantly reduced risk of breast cancer risk in women with the highest melatonin levels. Evidence for modulation of melatonin secretion in men with benign and malignant tumors of the prostate: Reduced cancer incidence among the blind. A total of women developed medical record—confirmed invasive endometrial cancer. As a more indirect mechanistic pathway, an effect of melatonin on fat metabolism has been described in relation to its cancer protective effects. Hitomi Tanaka Sleeping Beauty 24 min Vdoxies - 3. Night shift work and breast cancer risk Evidence from ecologic studies suggesting a lower breast cancer rate in women living in presumably darker Arctic regions, these observations led to the hypothesis that environmental light is related to cancer risk.